Philadelphia Phillies vs Houston Astros Betting Prediction and Best Bets for October 5

Rob Senior shares his expert MLB knowledge with a Philadelphia Phillies vs Houston Astros preview, prediction and best bet for October 5, 2022.

Maybe the best matchup of the final day of the 2022 MLB regular season is this interleague contest between two playoff teams.

Philadelphia is heading to the playoffs for the first time since 2011, while the Astros have clinched home-field advantage through the American League playoffs.

Here’s a look at Wednesday’s game:

Date & TimeWednesday, October 5, 4:10 P.M. Eastern
MoneylinePhiladelphia Phillies (+150) at Houston Astros (-180)
RunlinePhillies +1.5 (-140)/Astros -1.5 (+110)
TotalOver 7.5 (+105)/Under 7.5 (-115)
WhereMinute Maid Park, Houston, TX
WeatherRetractable Roof
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Season Series: So far in 2022, the Phillies and Astros are tied 1-1 in head-to-head matchups.

Starting Pitchers: Bailey Falter (6-4, 3.90 ERA) vs. Framber Valdez (16-6, 2.89 ERA)

Philadelphia Phillies Preview

Uncertainty is the word of the day for Phillies lefthander Bailey Falter, who could pitch as a starter or reliever in the upcoming playoffs.

Falter hasn’t appeared against the Astros this season but went six shutout innings in his last outing on Friday.

The Phillies’ lineup has been crushing left-handed pitchers of late, with a .778 OPS and overall .267 batting average vs. southpaws.

Houston Astros Preview

Framber Valdez isn’t just any lefty, with his ERA below 3 and having allowed only 11 home runs in the 2022 season.

Valdez figures to be a challenging matchup for a power-reliant Philadelphia lineup.

Houston has continued playing their starters since clinching their playoff position, and the lineup broke out in a big way with a five-run first inning in Tuesday night’s 10-0 victory over Philadelphia.

Philadelphia Phillies vs Houston Astros Prediction October 5, 2022

Falter has something to prove as he looks to earn his spot on the postseason roster, while Valdez figures to challenge Philadelphia’s power hitters.

Add to that the possibility of starters resting of leaving the game early with the playoffs around the corner and the solid late-season performances of both bullpens, and a low-scoring game appears to be in order.

Philadelphia Phillies vs Houston Astros Betting Pick October 5, 2022

Pick: Philadelphia Phillies/Houston Astros under 7.5 runs (-115)

Phillies vs Astros Betting Pick
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